Post-translational insertion of boron in proteins to probe and modulate function

Boron is absent in proteins, yet is a micronutrient. It possesses unique bonding that could expand biological function including modes of Lewis acidity not available to typical elements of life. Here we show that post-translational Cβ–Bγ bond formation provides mild, direct, site-selective access to...

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Detalles Bibliográficos
Autores principales: Mollner, Tim A., Isenegger, Patrick G., Josephson, Brian, Buchanan, Charles, Lercher, Lukas, Oehlrich, Daniel, Hansen, D. Flemming, Mohammed, Shabaz, Baldwin, Andrew J., Gouverneur, Véronique, Davis, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604732/
https://www.ncbi.nlm.nih.gov/pubmed/34725511
http://dx.doi.org/10.1038/s41589-021-00883-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604732/
https://www.ncbi.nlm.nih.gov/pubmed/34725511
http://dx.doi.org/10.1038/s41589-021-00883-7

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