Selective sodium iodide symporter (NIS) genetherapy of glioblastoma mediatedby EGFR-targeted lipopolyplexes

Lipo-oligomers, post-functionalized with ligands to enhance targeting, represent promising new vehicles for the tumor-specific delivery of therapeutic genes such as the sodium iodide symporter (NIS). Due to its iodide trapping activity, NIS is a powerful theranostic tool for diagnostic imaging and t...

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Detalles Bibliográficos
Autores principales: Spellerberg, Rebekka, Benli-Hoppe, Teoman, Kitzberger, Carolin, Berger, Simone, Schmohl, Kathrin A., Schwenk, Nathalie, Yen, Hsi-Yu, Zach, Christian, Schilling, Franz, Weber, Wolfgang A., Kälin, Roland E., Glass, Rainer, Nelson, Peter J., Wagner, Ernst, Spitzweg, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604759/
https://www.ncbi.nlm.nih.gov/pubmed/34853814
http://dx.doi.org/10.1016/j.omto.2021.10.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604759/
https://www.ncbi.nlm.nih.gov/pubmed/34853814
http://dx.doi.org/10.1016/j.omto.2021.10.011

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