Bile acids contribute to the development of non-alcoholic steatohepatitis in mice

BACKGROUND & AIMS: Through FXR and TGR5 signaling, bile acids (BAs) modulate lipid and glucose metabolism, inflammation and fibrosis. Hence, BAs returning to the liver after enteric secretion, modification and reabsorption may contribute to the pathogenesis of non-alcoholic steatohepatitis (NASH...

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Detalles Bibliográficos
Autores principales: Gillard, Justine, Clerbaux, Laure-Alix, Nachit, Maxime, Sempoux, Christine, Staels, Bart, Bindels, Laure B., Tailleux, Anne, Leclercq, Isabelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604813/
https://www.ncbi.nlm.nih.gov/pubmed/34825156
http://dx.doi.org/10.1016/j.jhepr.2021.100387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604813/
https://www.ncbi.nlm.nih.gov/pubmed/34825156
http://dx.doi.org/10.1016/j.jhepr.2021.100387

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