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Bile acids contribute to the development of non-alcoholic steatohepatitis in mice
BACKGROUND & AIMS: Through FXR and TGR5 signaling, bile acids (BAs) modulate lipid and glucose metabolism, inflammation and fibrosis. Hence, BAs returning to the liver after enteric secretion, modification and reabsorption may contribute to the pathogenesis of non-alcoholic steatohepatitis (NASH...
Autores principales: | Gillard, Justine, Clerbaux, Laure-Alix, Nachit, Maxime, Sempoux, Christine, Staels, Bart, Bindels, Laure B., Tailleux, Anne, Leclercq, Isabelle A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604813/ https://www.ncbi.nlm.nih.gov/pubmed/34825156 http://dx.doi.org/10.1016/j.jhepr.2021.100387 |
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