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The effects of hyperuricemia on endothelial cells are mediated via GLUT9 and the JAK2/STAT3 pathway

BACKGROUND: Uric acid (UA) transporters mediate the uptake and outflow of UA, and are greatly involved in the control of UA concentrations. Glucose transporter 9 (GLUT9), one of the UA transporters, has been confirmed to be expressed in human umbilical vein endothelial cells (HUVECs). This study aim...

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Detalles Bibliográficos
Autores principales: Nie, Qian, Liu, Miaomiao, Zhang, Zhimei, Zhang, Xuemei, Wang, Chao, Song, Guangyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604859/
https://www.ncbi.nlm.nih.gov/pubmed/34716863
http://dx.doi.org/10.1007/s11033-021-06840-w