Physiological significance of WDR45, a responsible gene for β-propeller protein associated neurodegeneration (BPAN), in brain development

WDR45 plays an essential role in the early stage of autophagy. De novo heterozygous mutations in WDR45 have been known to cause β-propeller protein-associated neurodegeneration (BPAN), a subtype of neurodegeneration with brain iron accumulation (NBIA). Although BPAN patients display global developme...

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Detalles Bibliográficos
Autores principales: Noda, Mariko, Ito, Hidenori, Nagata, Koh-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604945/
https://www.ncbi.nlm.nih.gov/pubmed/34799629
http://dx.doi.org/10.1038/s41598-021-02123-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604945/
https://www.ncbi.nlm.nih.gov/pubmed/34799629
http://dx.doi.org/10.1038/s41598-021-02123-3

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