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Plasmodium sporozoite phospholipid scramblase interacts with mammalian carbamoyl-phosphate synthetase 1 to infect hepatocytes

After inoculation by the bite of an infected mosquito, Plasmodium sporozoites enter the blood stream and infect the liver, where each infected cell produces thousands of merozoites. These in turn, infect red blood cells and cause malaria symptoms. To initiate a productive infection, sporozoites must...

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Detalles Bibliográficos
Autores principales: Cha, Sung-Jae, Kim, Min-Sik, Na, Chan Hyun, Jacobs-Lorena, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604956/
https://www.ncbi.nlm.nih.gov/pubmed/34799567
http://dx.doi.org/10.1038/s41467-021-27109-7