Identification of ligand binding sites in intrinsically disordered proteins with a differential binding score

Screening ligands directly binding to an ensemble of intrinsically disordered proteins (IDP) to discover potential hits or leads for new drugs is an emerging but challenging area as IDPs lack well-defined and ordered 3D-protein structures. To explore a new IDP-based rational drug discovery strategy,...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Qiao-Hong, Krishnan, V. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604960/
https://www.ncbi.nlm.nih.gov/pubmed/34799573
http://dx.doi.org/10.1038/s41598-021-00869-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604960/
https://www.ncbi.nlm.nih.gov/pubmed/34799573
http://dx.doi.org/10.1038/s41598-021-00869-4

Ejemplares similares