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A glucagon analogue decreases body weight in mice via signalling in the liver

Glucagon receptor agonists show promise as components of next generation metabolic syndrome pharmacotherapies. However, the biology of glucagon action is complex, controversial, and likely context dependent. As such, a better understanding of chronic glucagon receptor (GCGR) agonism is essential to...

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Detalles Bibliográficos
Autores principales: Hinds, Charlotte E., Owen, Bryn M., Hope, David C. D., Pickford, Philip, Jones, Ben, Tan, Tricia M., Minnion, James S., Bloom, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604983/
https://www.ncbi.nlm.nih.gov/pubmed/34799628
http://dx.doi.org/10.1038/s41598-021-01912-0