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piR-39980 mediates doxorubicin resistance in fibrosarcoma by regulating drug accumulation and DNA repair
Resistance to doxorubicin (DOX) is an obstacle to successful sarcoma treatment and a cause of tumor relapse, with the underlying molecular mechanism still unknown. PIWI-interacting RNAs (piRNAs) have been shown to enhance patient outcomes in cancers. However, there are few or no reports on piRNAs af...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605029/ https://www.ncbi.nlm.nih.gov/pubmed/34799689 http://dx.doi.org/10.1038/s42003-021-02844-1 |