Cargando…

piR-39980 mediates doxorubicin resistance in fibrosarcoma by regulating drug accumulation and DNA repair

Resistance to doxorubicin (DOX) is an obstacle to successful sarcoma treatment and a cause of tumor relapse, with the underlying molecular mechanism still unknown. PIWI-interacting RNAs (piRNAs) have been shown to enhance patient outcomes in cancers. However, there are few or no reports on piRNAs af...

Descripción completa

Detalles Bibliográficos
Autores principales: Das, Basudeb, Jain, Neha, Mallick, Bibekanand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605029/
https://www.ncbi.nlm.nih.gov/pubmed/34799689
http://dx.doi.org/10.1038/s42003-021-02844-1