Structure network-based landscape of rhodopsin misfolding by mutations and algorithmic prediction of small chaperone action

Failure of a protein to achieve its functional structural state and normal cellular location contributes to the etiology and pathology of heritable human conformational diseases. The autosomal dominant form of retinitis pigmentosa (adRP) is an incurable blindness largely linked to mutations of the m...

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Detalles Bibliográficos
Autores principales: Felline, Angelo, Schiroli, Davide, Comitato, Antonella, Marigo, Valeria, Fanelli, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605067/
https://www.ncbi.nlm.nih.gov/pubmed/34849206
http://dx.doi.org/10.1016/j.csbj.2021.10.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605067/
https://www.ncbi.nlm.nih.gov/pubmed/34849206
http://dx.doi.org/10.1016/j.csbj.2021.10.040

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