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Structure network-based landscape of rhodopsin misfolding by mutations and algorithmic prediction of small chaperone action
Failure of a protein to achieve its functional structural state and normal cellular location contributes to the etiology and pathology of heritable human conformational diseases. The autosomal dominant form of retinitis pigmentosa (adRP) is an incurable blindness largely linked to mutations of the m...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605067/ https://www.ncbi.nlm.nih.gov/pubmed/34849206 http://dx.doi.org/10.1016/j.csbj.2021.10.040 |