Production of human CAR-NK cells with lentiviral vectors and functional assessment in vitro

Although natural killer (NK) cells have become a promising immune effector cell for chimeric antigen receptor (CAR)-based therapy, generating human CAR-NK cells with high transgene efficiency has been challenging. In this protocol, we describe how to generate CAR-NK cells with transduction efficienc...

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Detalles Bibliográficos
Autores principales: Portillo, Ana L., Hogg, Richard, Ashkar, Ali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605094/
https://www.ncbi.nlm.nih.gov/pubmed/34825217
http://dx.doi.org/10.1016/j.xpro.2021.100956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605094/
https://www.ncbi.nlm.nih.gov/pubmed/34825217
http://dx.doi.org/10.1016/j.xpro.2021.100956

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