Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anticancer activities in lung adenocarcinoma

Within the superfamily of small GTPases, Ras appears to be the master regulator of such processes as cell cycle progression, cell division, and apoptosis. Several oncogenic Ras mutations at amino acid positions 12, 13, and 61 have been identified that lose their ability to hydrolyze GTP, giving rise...

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Detalles Bibliográficos
Autores principales: Singh, Anamika, Erijman, Ariel, Noronha, Ashish, Kumar, Hemant, Peleg, Yoav, Yarden, Yosef, Shifman, Julia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605244/
https://www.ncbi.nlm.nih.gov/pubmed/34717958
http://dx.doi.org/10.1016/j.jbc.2021.101353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605244/
https://www.ncbi.nlm.nih.gov/pubmed/34717958
http://dx.doi.org/10.1016/j.jbc.2021.101353

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