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β-cell Smad2 null mice have improved β-cell function and are protected from diet-induced hyperglycemia
Understanding signaling pathways that regulate pancreatic β-cell function to produce, store, and release insulin, as well as pathways that control β-cell proliferation, is vital to find new treatments for diabetes mellitus. Transforming growth factor-beta (TGF-β) signaling is involved in a broad ran...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605249/ https://www.ncbi.nlm.nih.gov/pubmed/34582892 http://dx.doi.org/10.1016/j.jbc.2021.101235 |