β-cell Smad2 null mice have improved β-cell function and are protected from diet-induced hyperglycemia

Understanding signaling pathways that regulate pancreatic β-cell function to produce, store, and release insulin, as well as pathways that control β-cell proliferation, is vital to find new treatments for diabetes mellitus. Transforming growth factor-beta (TGF-β) signaling is involved in a broad ran...

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Detalles Bibliográficos
Autores principales: Saleh, Mohamed, Mohamed, Nada A., Sehrawat, Anuradha, Zhang, Ting, Thomas, Madison, Wang, Yan, Kalsi, Ranjeet, Molitoris, Justin, Prasadan, Krishna, Gittes, George K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605249/
https://www.ncbi.nlm.nih.gov/pubmed/34582892
http://dx.doi.org/10.1016/j.jbc.2021.101235

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