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PHF5A promotes colorectal cancerprogression by alternative splicing of TEAD2

Dysregulated alternative splicing (AS) plays critical roles in driving cancer progression, and the underlying mechanisms remain largely unknown. Here, we demonstrated that PHF5A, a component of U2 small nuclear ribonucleoproteins, was frequently upregulated in colorectal cancer (CRC) samples and ass...

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Detalles Bibliográficos
Autores principales: Chang, Yue, Zhao, Yulu, Wang, Liya, Wu, Meijuan, He, Chenglong, Huang, Mengxi, Lei, Zengjie, Yang, Jiahe, Han, Siqi, Wang, Bibo, Chen, Yanyan, Liu, Chao, Yu, Hongju, Xue, Lijun, Geng, Jian, Chen, Yanan, Dai, Tingting, Ren, Lili, Wang, Qian, Liu, Xiaobei, Chu, Xiaoyuan, Chen, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605294/
https://www.ncbi.nlm.nih.gov/pubmed/34853721
http://dx.doi.org/10.1016/j.omtn.2021.10.025