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Stabilization of the classical phenotype upon integration of pancreatic cancer cells into the duodenal epithelium

INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive solid tumors. Based on transcriptomic classifiers, basal-like and classical PDAC subtypes have been defined that differ in prognosis. Cells of both subtypes can coexist in individual tumors; however, the contribution...

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Detalles Bibliográficos
Autores principales: Bozóky, Benedek, Moro, Fernández, Strell, Carina, Geyer, Natalie, Heuchel, Rainer L., Löhr, J. Matthias, Ernberg, Ingemar, Szekely, Laszlo, Gerling, Marco, Bozóky, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605302/
https://www.ncbi.nlm.nih.gov/pubmed/34798385
http://dx.doi.org/10.1016/j.neo.2021.11.007