Up-regulation of ubiquitin–proteasome activity upon loss of NatA-dependent N-terminal acetylation

N-terminal acetylation is a prominent protein modification, and inactivation of N-terminal acetyltransferases (NATs) cause protein homeostasis stress. Using multiplexed protein stability profiling with linear ubiquitin fusions as reporters for the activity of the ubiquitin proteasome system, we obse...

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Detalles Bibliográficos
Autores principales: Kats, Ilia, Reinbold, Christian, Kschonsak, Marc, Khmelinskii, Anton, Armbruster, Laura, Ruppert, Thomas, Knop, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605321/
https://www.ncbi.nlm.nih.gov/pubmed/34764209
http://dx.doi.org/10.26508/lsa.202000730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605321/
https://www.ncbi.nlm.nih.gov/pubmed/34764209
http://dx.doi.org/10.26508/lsa.202000730

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