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Up-regulation of ubiquitin–proteasome activity upon loss of NatA-dependent N-terminal acetylation
N-terminal acetylation is a prominent protein modification, and inactivation of N-terminal acetyltransferases (NATs) cause protein homeostasis stress. Using multiplexed protein stability profiling with linear ubiquitin fusions as reporters for the activity of the ubiquitin proteasome system, we obse...
Autores principales: | Kats, Ilia, Reinbold, Christian, Kschonsak, Marc, Khmelinskii, Anton, Armbruster, Laura, Ruppert, Thomas, Knop, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605321/ https://www.ncbi.nlm.nih.gov/pubmed/34764209 http://dx.doi.org/10.26508/lsa.202000730 |
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