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Targeting myeloid-derived suppressor cells to attenuate vasculogenic mimicry and synergistically enhance the anti-tumor effect of PD-1 inhibitor

Myeloid-derived suppressor cells (MDSCs) enhance the proliferation of endothelial cells to stimulate angiogenesis. However, many aggressive malignant tumors do not have endothelial cell-dependent blood vessels in the early stage and instead generate microcirculation by forming vasculogenic mimicry (...

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Detalles Bibliográficos
Autores principales: Li, Yinan, Qiao, Kailiang, Zhang, Xiaoyun, Liu, Haoyang, Zhang, Heng, Li, Zhiyang, Liu, Yanrong, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605339/
https://www.ncbi.nlm.nih.gov/pubmed/34841231
http://dx.doi.org/10.1016/j.isci.2021.103392