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The role of protease-activated receptor 1 signaling in CD8 T cell effector functions

CD8 T cells are essential for adaptive immunity against viral infections. Protease activated receptor 1 (PAR1) is expressed by CD8 T cells; however, its role in T cell effector function is not well defined. Here we show that in human CD8 T cells, PAR1 stimulation accelerates calcium mobilization. Fu...

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Detalles Bibliográficos
Autores principales: Chen, Hui, Smith, Mindy, Herz, Jasmin, Li, Tong, Hasley, Rebecca, Le Saout, Cecile, Zhu, Ziang, Cheng, Jie, Gronda, Andres, Martina, José A., Irusta, Pablo M., Karpova, Tatiana, McGavern, Dorian B., Catalfamo, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605340/
https://www.ncbi.nlm.nih.gov/pubmed/34841225
http://dx.doi.org/10.1016/j.isci.2021.103387