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The role of protease-activated receptor 1 signaling in CD8 T cell effector functions

CD8 T cells are essential for adaptive immunity against viral infections. Protease activated receptor 1 (PAR1) is expressed by CD8 T cells; however, its role in T cell effector function is not well defined. Here we show that in human CD8 T cells, PAR1 stimulation accelerates calcium mobilization. Fu...

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Detalles Bibliográficos
Autores principales:	Chen, Hui, Smith, Mindy, Herz, Jasmin, Li, Tong, Hasley, Rebecca, Le Saout, Cecile, Zhu, Ziang, Cheng, Jie, Gronda, Andres, Martina, José A., Irusta, Pablo M., Karpova, Tatiana, McGavern, Dorian B., Catalfamo, Marta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605340/ https://www.ncbi.nlm.nih.gov/pubmed/34841225 http://dx.doi.org/10.1016/j.isci.2021.103387

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