Supramolecular polymer-based transformable material for reversible PEGylation of protein drugs

We herein developed a transformable mixing-type material for reversible PEGylation of protein drugs using a supramolecular backbone polymer, that is, polyrotaxane possessing both amino groups and PEG chains (PEG–NH(2)–PRX). We expected that PEG–NH(2)–PRX provides amino groups to interact with protei...

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Detalles Bibliográficos
Autores principales: Utatsu, Kosei, Kogo, Tetsuya, Taharabaru, Toru, Onodera, Risako, Motoyama, Keiichi, Higashi, Taishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605344/
https://www.ncbi.nlm.nih.gov/pubmed/34841242
http://dx.doi.org/10.1016/j.mtbio.2021.100160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605344/
https://www.ncbi.nlm.nih.gov/pubmed/34841242
http://dx.doi.org/10.1016/j.mtbio.2021.100160

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