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Supramolecular polymer-based transformable material for reversible PEGylation of protein drugs
We herein developed a transformable mixing-type material for reversible PEGylation of protein drugs using a supramolecular backbone polymer, that is, polyrotaxane possessing both amino groups and PEG chains (PEG–NH(2)–PRX). We expected that PEG–NH(2)–PRX provides amino groups to interact with protei...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605344/ https://www.ncbi.nlm.nih.gov/pubmed/34841242 http://dx.doi.org/10.1016/j.mtbio.2021.100160 |