Oxidation sensitizes TRPV2 to chemical and heat stimuli, but not mechanical stimulation

The transient receptor potential vanilloid 2 (TRPV2) ion channel is activated by a chemical ligand (2-aminoethoxydiphenyl borate; 2-APB), noxious heat and mechanical stimulation. In a heterologous mammalian cell expression system, the oxidant chloramine T (ChT) sensitizes TRPV2 activation in respons...

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Detalles Bibliográficos
Autores principales: Oda, Mai, Fujiwara, Yuichiro, Ishizaki, Yasuki, Shibasaki, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605382/
https://www.ncbi.nlm.nih.gov/pubmed/34841092
http://dx.doi.org/10.1016/j.bbrep.2021.101173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605382/
https://www.ncbi.nlm.nih.gov/pubmed/34841092
http://dx.doi.org/10.1016/j.bbrep.2021.101173

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