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Overexpression of E3 ubiquitin ligase Cbl attenuates endothelial dysfunction in diabetes mellitus by inhibiting the JAK2/STAT4 signaling and Runx3-mediated H3K4me3

BACKGROUND: Diabetes mellitus (DM), a most common chronic disease, is featured with impaired endothelial function and bioavailability of nitric oxide (NO), while E3 ubiquitin ligase appears to alleviate endothelial dysfunction as a promising option for DM treatment. Herein, we aimed to determine whe...

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Detalles Bibliográficos
Autores principales:	Jin, Qingsong, Lin, Liangyan, Zhao, Tiantian, Yao, Xiaoyan, Teng, Yaqin, Zhang, Dongdong, Jin, Yongjun, Yang, Meizi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605525/ https://www.ncbi.nlm.nih.gov/pubmed/34798872 http://dx.doi.org/10.1186/s12967-021-03069-w

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