Colistin resistance in Gram-negative bacteria analysed by five phenotypic assays and inference of the underlying genomic mechanisms

BACKGROUND: Colistin is used against multi-drug resistant pathogens, yet resistance emerges through dissemination of plasmid-mediated genes (mcr) or chromosomal mutation of genes involved in lipopolysaccharide synthesis (i.e. mgrB, phoPQ, pmrCAB). Phenotypic susceptibility testing is challenging due...

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Detalles Bibliográficos
Autores principales: Torres, Diana Albertos, Seth-Smith, Helena M. B., Joosse, Nicole, Lang, Claudia, Dubuis, Olivier, Nüesch-Inderbinen, Magdalena, Hinic, Vladimira, Egli, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605564/
https://www.ncbi.nlm.nih.gov/pubmed/34798825
http://dx.doi.org/10.1186/s12866-021-02388-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605564/
https://www.ncbi.nlm.nih.gov/pubmed/34798825
http://dx.doi.org/10.1186/s12866-021-02388-8

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