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Colistin resistance in Gram-negative bacteria analysed by five phenotypic assays and inference of the underlying genomic mechanisms

BACKGROUND: Colistin is used against multi-drug resistant pathogens, yet resistance emerges through dissemination of plasmid-mediated genes (mcr) or chromosomal mutation of genes involved in lipopolysaccharide synthesis (i.e. mgrB, phoPQ, pmrCAB). Phenotypic susceptibility testing is challenging due...

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Detalles Bibliográficos
Autores principales:	Torres, Diana Albertos, Seth-Smith, Helena M. B., Joosse, Nicole, Lang, Claudia, Dubuis, Olivier, Nüesch-Inderbinen, Magdalena, Hinic, Vladimira, Egli, Adrian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605564/ https://www.ncbi.nlm.nih.gov/pubmed/34798825 http://dx.doi.org/10.1186/s12866-021-02388-8

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