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MiR-149-3p promotes the cisplatin resistance and EMT in ovarian cancer through downregulating TIMP2 and CDKN1A

BACKGROUND: Ovarian cancer (OC), a kind of gynecological cancer, is characterized by high mortality rate, with microRNAs (miRNAs) playing essential roles in it. However, the clinical significance of miRNAs and their molecular mechanisms in OC are mostly unknown. METHODS: miR-149-3p expression was pr...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Liu, Lingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605569/
https://www.ncbi.nlm.nih.gov/pubmed/34798882
http://dx.doi.org/10.1186/s13048-021-00919-5