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Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) causes substantial medical and societal burden with no therapies ameliorating cognitive deficits. Centralized pathologies involving amyloids, neurofibrillary tangles, and neuroinflammatory pathways are being investigated to identify disease-modifying targets for...

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Detalles Bibliográficos
Autores principales: Banik, Avijit, Amaradhi, Radhika, Lee, Daniel, Sau, Michael, Wang, Wenyi, Dingledine, Raymond, Ganesh, Thota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605573/
https://www.ncbi.nlm.nih.gov/pubmed/34801055
http://dx.doi.org/10.1186/s12974-021-02297-7