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Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer’s disease
BACKGROUND: Alzheimer’s disease (AD) causes substantial medical and societal burden with no therapies ameliorating cognitive deficits. Centralized pathologies involving amyloids, neurofibrillary tangles, and neuroinflammatory pathways are being investigated to identify disease-modifying targets for...
Autores principales: | Banik, Avijit, Amaradhi, Radhika, Lee, Daniel, Sau, Michael, Wang, Wenyi, Dingledine, Raymond, Ganesh, Thota |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605573/ https://www.ncbi.nlm.nih.gov/pubmed/34801055 http://dx.doi.org/10.1186/s12974-021-02297-7 |
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