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Telomerase subunit Est2 marks internal sites that are prone to accumulate DNA damage

BACKGROUND: The main function of telomerase is at the telomeres but under adverse conditions telomerase can bind to internal regions causing deleterious effects as observed in cancer cells. RESULTS: By mapping the global occupancy of the catalytic subunit of telomerase (Est2) in the budding yeast Sa...

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Detalles Bibliográficos
Autores principales: Pandey, Satyaprakash, Hajikazemi, Mona, Zacheja, Theresa, Schalbetter, Stephanie, Neale, Matthew J., Baxter, Jonathan, Guryev, Victor, Hofmann, Andreas, Heermann, Dieter W., Juranek, Stefan A., Paeschke, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605574/
https://www.ncbi.nlm.nih.gov/pubmed/34801008
http://dx.doi.org/10.1186/s12915-021-01167-1