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Telomerase subunit Est2 marks internal sites that are prone to accumulate DNA damage
BACKGROUND: The main function of telomerase is at the telomeres but under adverse conditions telomerase can bind to internal regions causing deleterious effects as observed in cancer cells. RESULTS: By mapping the global occupancy of the catalytic subunit of telomerase (Est2) in the budding yeast Sa...
Autores principales: | Pandey, Satyaprakash, Hajikazemi, Mona, Zacheja, Theresa, Schalbetter, Stephanie, Neale, Matthew J., Baxter, Jonathan, Guryev, Victor, Hofmann, Andreas, Heermann, Dieter W., Juranek, Stefan A., Paeschke, Katrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605574/ https://www.ncbi.nlm.nih.gov/pubmed/34801008 http://dx.doi.org/10.1186/s12915-021-01167-1 |
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