Cargando…

Caspase-3/NLRP3 signaling in the mesenchymal stromal niche regulates myeloid-biased hematopoiesis

BACKGROUND: The fate of hematopoietic stem cells (HSCs) is determined by a complex regulatory network that includes both intrinsic and extrinsic signals. In the past decades, many intrinsic key molecules of HSCs have been shown to control hematopoiesis homeostasis. Non-hematopoietic niche cells also...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jing, Chen, Yaozhen, Yin, Dandan, Feng, Fan, An, Qunxing, Liu, Zhixin, An, Ning, Xu, Jinmei, Yi, Jing, Gu, Shunli, Yin, Wen, Wang, Yazhou, Hu, Xingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605603/
https://www.ncbi.nlm.nih.gov/pubmed/34801085
http://dx.doi.org/10.1186/s13287-021-02640-y