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Caspase-3/NLRP3 signaling in the mesenchymal stromal niche regulates myeloid-biased hematopoiesis
BACKGROUND: The fate of hematopoietic stem cells (HSCs) is determined by a complex regulatory network that includes both intrinsic and extrinsic signals. In the past decades, many intrinsic key molecules of HSCs have been shown to control hematopoiesis homeostasis. Non-hematopoietic niche cells also...
Autores principales: | Zhang, Jing, Chen, Yaozhen, Yin, Dandan, Feng, Fan, An, Qunxing, Liu, Zhixin, An, Ning, Xu, Jinmei, Yi, Jing, Gu, Shunli, Yin, Wen, Wang, Yazhou, Hu, Xingbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605603/ https://www.ncbi.nlm.nih.gov/pubmed/34801085 http://dx.doi.org/10.1186/s13287-021-02640-y |
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