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Comparing the Clinical Utility and Diagnostic Performance of CSF P-Tau181, P-Tau217, and P-Tau231 Assays

BACKGROUND AND OBJECTIVES: Phosphorylated tau (p-tau) in CSF is considered an important biomarker in Alzheimer disease (AD) and has been incorporated in recent diagnostic criteria. Several variants exist, including p-tau at threonines 181 (p-tau181), 217 (p-tau217), and 231 (p-tau231). However, no s...

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Detalles Bibliográficos
Autores principales: Leuzy, Antoine, Janelidze, Shorena, Mattsson-Carlgren, Niklas, Palmqvist, Sebastian, Jacobs, Dirk, Cicognola, Claudia, Stomrud, Erik, Vanmechelen, Eugeen, Dage, Jeffrey L., Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605616/
https://www.ncbi.nlm.nih.gov/pubmed/34493616
http://dx.doi.org/10.1212/WNL.0000000000012727