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Shikonin Promotes Apoptosis and Attenuates Migration and Invasion of Human Esophageal Cancer Cells by Inhibiting Tumor Necrosis Factor Receptor-Associated Protein 1 Expression and AKT/mTOR Signaling Pathway

The aim of this study was to investigate the anticancer effects of shikonin on esophageal cancer (EC) cells and explore the underlying molecular mechanism by identifying dysregulation in shikonin-induced tumor necrosis factor receptor-associated protein 1 (TRAP1) expression. The 3-(4, 5-dimethylthia...

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Detalles Bibliográficos
Autores principales: Huang, Jingrong, Zhao, Li, Gong, Chengxian, Wang, Yi, Qu, Yinzong, Ji, Chunyan, Yang, Jianmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8605926/
https://www.ncbi.nlm.nih.gov/pubmed/34812264
http://dx.doi.org/10.1155/2021/5386050