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Morphological predictors for microsatellite instability in urothelial carcinoma

INTRODUCTION: Microsatellite instability occurs due to a series of mutations in the DNA pairing error repair (Mismatch repair; MMR) genes, which can affect germ cells as occurs in Lynch syndrome, whose patients are at high risk of developing multiple cancers. The loss of MMR protein is commonly dete...

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Detalles Bibliográficos
Autores principales: Sobrino-Reig, Eduardo, Meizoso, Telma, García, Jesús, Varillas-Delgado, David, Martin, Yasmina B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606048/
https://www.ncbi.nlm.nih.gov/pubmed/34801034
http://dx.doi.org/10.1186/s13000-021-01168-2