Leucine imparts cardioprotective effects by enhancing mTOR activity and mitochondrial fusion in a myocardial ischemia/reperfusion injury murine model

BACKGROUND: Coronary artery disease is a leading cause of morbidity and mortality among patients with diabetes. Previously, we demonstrated that branched-chain amino acids (BCAAs) showed cardioprotective effects against cardiac ischemia/reperfusion (I/R) injury. A recent study suggested that leucine...

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Detalles Bibliográficos
Autores principales: Morio, Atsushi, Tsutsumi, Rie, Satomi, Shiho, Kondo, Takashi, Miyoshi, Hirotsugu, Kato, Takahiro, Kuroda, Masashi, Kitamura, Tadahiro, Hara, Kenta, Saeki, Noboru, Sakaue, Hiroshi, Tsutsumi, Yasuo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606064/
https://www.ncbi.nlm.nih.gov/pubmed/34801078
http://dx.doi.org/10.1186/s13098-021-00755-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606064/
https://www.ncbi.nlm.nih.gov/pubmed/34801078
http://dx.doi.org/10.1186/s13098-021-00755-z

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