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On clinical trial fragility due to patients lost to follow up

BACKGROUND: Clinical trials routinely have patients lost to follow up. We propose a methodology to understand their possible effect on the results of statistical tests by altering the concept of the fragility index to treat the outcomes of observed patients as fixed but incorporate the potential out...

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Detalles Bibliográficos
Autores principales: Baer, Benjamin R., Fremes, Stephen E., Gaudino, Mario, Charlson, Mary, Wells, Martin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606097/
https://www.ncbi.nlm.nih.gov/pubmed/34800976
http://dx.doi.org/10.1186/s12874-021-01446-z