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On clinical trial fragility due to patients lost to follow up
BACKGROUND: Clinical trials routinely have patients lost to follow up. We propose a methodology to understand their possible effect on the results of statistical tests by altering the concept of the fragility index to treat the outcomes of observed patients as fixed but incorporate the potential out...
Autores principales: | Baer, Benjamin R., Fremes, Stephen E., Gaudino, Mario, Charlson, Mary, Wells, Martin T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606097/ https://www.ncbi.nlm.nih.gov/pubmed/34800976 http://dx.doi.org/10.1186/s12874-021-01446-z |
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