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A Cross-Sectional Study for Evaluation of KRAS and BRAF Mutations by Reverse Dot Blot, PCR-RFLP, and Allele-Specific PCR Methods Among Patients with Colorectal Cancer

BACKGROUND: KRAS and BRAF genes are the biomarkers in Colorectal Cancer (CRC) which play prognostic and predictive roles in CRC treatment. Nowadays, the selection of rapid and available methods for studying KRAS and BRAF mutations in anti-EGFR therapy of patients suffering from CRC plays a significa...

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Detalles Bibliográficos
Autores principales: Sheikhsofla, Fatemeh, Poopak, Behzad, Firuzyar, Sajjad, Roudbari, Fatemeh, Ghadiany, Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606106/
https://www.ncbi.nlm.nih.gov/pubmed/34900144