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Alteration of PPAR‐GAMMA (PPARG; PPARγ) and PTEN gene expression in acute myeloid leukemia patients and the promising anticancer effects of PPARγ stimulation using pioglitazone on AML cells

BACKGROUND: In the new era of tailored cancer treatment strategies, finding a molecule to regulate a wide range of intracellular functions is valuable. The unique property of nuclear receptor peroxisome proliferator‐activated receptor‐γ (PPARγ; PPARG) in transmitting the anti‐survival signals of the...

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Detalles Bibliográficos
Autores principales: Esmaeili, Shadi, Salari, Sina, Kaveh, Vahid, Ghaffari, Seyed H., Bashash, Davood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606220/
https://www.ncbi.nlm.nih.gov/pubmed/34549887
http://dx.doi.org/10.1002/mgg3.1818