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Quantification of cell-free DNAfor the analysis of CD19-CAR-T cells during lymphoma treatment

Chimeric antigen receptor (CAR)-T cells are increasingly used for the treatment of hematologic malignancies. Treatment success relies highly upon sufficient expansion of CAR-T effector cells. Accordingly, longitudinal quantification of CAR-T cells during therapy is clinically important. Techniques t...

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Detalles Bibliográficos
Autores principales: Mika, Thomas, Thomson, Julia, Nilius-Eliliwi, Verena, Vangala, Deepak, Baraniskin, Alexander, Wulf, Gerald, Klein-Scory, Susanne, Schroers, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606297/
https://www.ncbi.nlm.nih.gov/pubmed/34853800
http://dx.doi.org/10.1016/j.omtm.2021.10.009