Loss of immune homeostasis in patients with idiopathic pulmonary arterial hypertension

INTRODUCTION: Autoreactivity against pulmonary vascular structures is thought to be involved in idiopathic pulmonary arterial hypertension (IPAH), but the underlying mechanisms remain poorly understood. We hypothesised that aberrant B-cell activation contributes to IPAH aetiology. METHODS: Mice with...

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Detalles Bibliográficos
Autores principales: Heukels, Peter, Corneth, Odilia B J, van Uden, Denise, van Hulst, Jennifer A C, van den Toorn, Leon M, van den Bosch, Annemien E, Wijsenbeek, Marlies S, Boomars, Karin A, Kool, Mirjam, Hendriks, Rudi W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Pulmonary Vasculature
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606455/
https://www.ncbi.nlm.nih.gov/pubmed/33963088
http://dx.doi.org/10.1136/thoraxjnl-2020-215460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606455/
https://www.ncbi.nlm.nih.gov/pubmed/33963088
http://dx.doi.org/10.1136/thoraxjnl-2020-215460

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