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Loss of immune homeostasis in patients with idiopathic pulmonary arterial hypertension

INTRODUCTION: Autoreactivity against pulmonary vascular structures is thought to be involved in idiopathic pulmonary arterial hypertension (IPAH), but the underlying mechanisms remain poorly understood. We hypothesised that aberrant B-cell activation contributes to IPAH aetiology. METHODS: Mice with...

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Detalles Bibliográficos
Autores principales:	Heukels, Peter, Corneth, Odilia B J, van Uden, Denise, van Hulst, Jennifer A C, van den Toorn, Leon M, van den Bosch, Annemien E, Wijsenbeek, Marlies S, Boomars, Karin A, Kool, Mirjam, Hendriks, Rudi W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Pulmonary Vasculature
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606455/ https://www.ncbi.nlm.nih.gov/pubmed/33963088 http://dx.doi.org/10.1136/thoraxjnl-2020-215460

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