Sphingosine Kinase 1 Signaling in Breast Cancer: A Potential Target to Tackle Breast Cancer Stem Cells

Sphingosine kinases (SPHKs) are conserved lipid enzymes that catalyze the formation of sphingosine-1-phosphate (S1P) through ATP-dependent phosphorylation of sphingosine. Two distinct SPHK isoforms, namely SPHK1 and SPHK2, have been identified to date, and the former has been implicated for its onco...

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Detalles Bibliográficos
Autores principales: Hii, Ling-Wei, Chung, Felicia Fei-Lei, Mai, Chun-Wai, Ng, Pei Yuen, Leong, Chee-Onn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606534/
https://www.ncbi.nlm.nih.gov/pubmed/34820423
http://dx.doi.org/10.3389/fmolb.2021.748470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606534/
https://www.ncbi.nlm.nih.gov/pubmed/34820423
http://dx.doi.org/10.3389/fmolb.2021.748470

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