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Quantitative Analysis of the Efficacy of PARP Inhibitors as Maintenance Therapy in Recurrent Ovarian Cancer

Objective: This study aimed to establish a pharmacodynamic model and to screen reasonable covariates to quantitatively describe the efficacy of poly (ADP-ribose) polymerase inhibitors (PARPis) as maintenance treatment for recurrent ovarian cancer (ROC). Methods: The log normal hazard function model...

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Detalles Bibliográficos
Autores principales: Gao, Lili, Chen, Rui, Li, Ting, Li, Lujin, Zheng, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606554/
https://www.ncbi.nlm.nih.gov/pubmed/34819864
http://dx.doi.org/10.3389/fphar.2021.771836