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Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation

Transthyretin (TTR), a plasma and cerebrospinal fluid protein, increases axon growth and organelle transport in sensory neurons. While neurons extend their axons, the microtubule (MT) cytoskeleton is crucial for the segregation of functional compartments and axonal outgrowth. Herein, we investigated...

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Detalles Bibliográficos
Autores principales: Eira, Jessica, Magalhães, Joana, Macedo, Nídia, Pero, Maria Elena, Misgeld, Thomas, Sousa, Mónica M., Bartolini, Francesca, Liz, Márcia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8606651/
https://www.ncbi.nlm.nih.gov/pubmed/34820375
http://dx.doi.org/10.3389/fcell.2021.747699